David W.A. Bourne, Ph.D. Professor of Pharmaceutics

Department of Pharmaceutical Sciences
College of Pharmacy
The University of Oklahoma - Health Sciences Center

Office: CPB 303
1110 N. Stonewall Ave, Oklahoma City, OK 73117-1223
Telephone: (405) 271-6481,X 47213 FAX: 405 271-7505
Email address: david-bourne@ouhsc.edu

Education and Training

Diploma of Pharmacy, Victorian College of Pharmacy, 1967
B.Pharm., Victorian Institute of Colleges, 1971
M.S. (Honors), University of Kansas, 1973
Ph.D., University of Kansas - Victorian College of Pharmacy (Intersearch) 1974. Thesis, "Acronycine esters as Pro-Drugs. Inhibition of Hydrolysis by Complexation"
Postdoctoral Fellow, College of Pharmacy, University of Kentucky, Lexington, 1974 - 1977

Research Interests

Recent Publications

• Smith, C.L., Hampton, E.M., Pederson, J.A., Pennington, L.R., and Bourne, D.W.A., 1994 Clinical and Medicoeconomic Impact of the Cyclosporine-Diltiazem Interaction in Renal Transplant Recipients, Pharmacotherapy, 14(4), 471-481
• Srinivasan, R.S., Bourne, D.W.A., and Putcha, L. 1994 Application of Physiologically Based Pharmacokinetic Models for Assessing Drug Disposition in Space, J. Clin. Pharmacol., 34, 692-698
• Walker, J.L., Clarke, C.R., Hague, C.M., Bourne, D.W.A., and Lessley, B.A. 1994 Effects of Localized Pastereurella haemolytica Infection on Erythromycin-Binding Properties of Bovine Alpha-1-Acid Glycoprotein, Albumin, Serum, and Tissue Chamber Fluids, Antimicrobial Agents and Chemotherapy, 38(10), 2392-2397
• Whipple L.K., Lewis, K.S., Weitman, S.D., Ausman, R.K., Bourne, D.W.A., Andrews, W., Adams, M.B., Sasse, E.A., Quebbeman, E.J. 1994 Pharmacokinetic Evaluation of a New Oral Cyclosporine Formulation, Pharmacotherapy, 14(1), 105-110
• Bourne, D.W.A., 1995 Mathematical Modeling of Pharmacokinetic Data, Technomic Publishing Co., Lancaster, PA
• Bourne, D.W.A., and Dittert, L.W. 1995 Pharmacokinetics. In Modern Pharmaceutics. Banker, G.S. and Rhodes, C.T. eds, 3rd ed., Marcel Dekker, New York, NY
• Chen, C.L., Sangiah, S., Bourne, D.W.A., Roder J.D., Chen, H., Alavi, F.K., Clarke, C.R., Garrison, G.L., Berlin, K.D., Couch, K.M., Zisman, S.A., Scherlag, B.J. , Lazzara R. and Van Der Helm, D. 1995 In vivo and in vitro Metabolism Studies on 7-Benzyl-3-thia-7-azabicyclo[3.3.1]nonane, an antiarrythmic agent, Eur. J. Drug Metab.and Pharmacokin., 20(2), 151-161
• Bourne, D.W.A., Hogkinson, P., McLean, S. 1995 A Trek Through CyberSpace, Amer. J. Pharm. Ed., 59, 402-408
• Bourne, D.W.A., 1996 Internet Pharmacy Resources, Basic Bibliographies, Hospital Pharmacy, 31, 594, 599
• Bourne, D.W.A., 1996 Web Resources: The American Association of Pharmaceutical Scientists (AAPS), Pharmaceutical Technology, 20(6), 115-116
• Doris, P.A., Hayward-Lester, A., Bourne, D.W.A., and Stocco, D.M. 1996 Ouabain Production by Cultured Adrenal Cells, Endocrinology, 137, 533-539
• Putcha, L., Tietze, K.J., Bourne, D.W.A., Parise, C.M., Hunter, R.P., Cintron, N.M. 1996 Bioavailability of Intranasal Scopolamine in Normal Subjects, J. Pharm. Sci., 85(8), 899-902
• Bourne, D.W.A., 1997 Using the Internet as a Pharmacokinetic Resource, Clinical Pharmacokinetics, 33, 153-160
• Kwon, K.I. and Bourne, D.W.A., 1997 Gastrointestinal Absorption of Phenytoin from an Oil-in-water Microemulsion, Arch. Pharm. Res., 20(5), 480-485
• Polikandritou Lambros, M., Bourne, D.W.A., Abbas, S.A., Johnson, D.L. 1997 Disposition of Aerosolized Liposomal Amphotericin B, J. Pharm. Sci., 86, 1066-1069

Courses

• PHAR 7632 Biopharmaceutics
• PHAR 7633 Pharmacokinetics
• Advanced Biopharmaceutics